Simulation of Cell Dielectric Properties Based on COMSOL

Authors
Shudong Li, Xiaoyan Chen, Fengze Han
Corresponding Author
Xiaoyan Chen
Available Online 31 March 2018.
DOI
https://doi.org/10.2991/jrnal.2018.4.4.16
Keywords
dielectric properties, cell model, excitation frequency, finite element method (FEM), auxiliary method
Abstract
The dielectric properties of cells can be observed by injecting a low amplitude current at different frequencies (1MHz~100MHz). The simulation research is taken on the software platform named COMSOL Multiphysics. The electric field and the cell model is created with prior information. By simulation, it’s verified that at low frequencies, the region of interest (ROI) behaves the conductivity characteristic while the electrical signal cannot pass through the cell membrane due to its capacitor properties. With the excitation frequency increasing, the ROI behaves more permittivity characteristic that the current flowing through the cell membrane becomes more and the current density increases. The research of the cell dielectric properties provides an auxiliary method to diagnose the status of the cell.

Copyright
© 2018, the Authors. Published by ALife Robotics Corp. Ltd.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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